Pub. Date : 2012 Sep
PMID : 22568685
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This study was designed to assess the contribution of different nAChR subtypes to the behavioural and neurochemical effects of chronic cocaine treatment. | Cocaine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 2 | Quantitative autoradiography was used to examine the effect of cocaine exposure on alpha7 and alpha4beta2* nAChRs, and on the high-affinity choline transporter. | Cocaine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 3 | KEY RESULTS: MLA+cocaine administration induced an intense self-grooming behaviour, indicating a likely role for alpha7 nAChRs in modulating this anxiogenic, compulsive-like effect of cocaine. | Cocaine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |