Title : Lack of nitric oxide synthases increases lipoprotein immune complex deposition in the aorta and elevates plasma sphingolipid levels in lupus.

Pub. Date : 2012 Mar-Apr

PMID : 22560558






1 Functional Relationships(s)
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1 NOS2 and NOS3 knockout (KO) MRL/lpr mice had higher plasma levels of triglycerides (23% and 35%, respectively), ceramide (45% and 21%, respectively), and sphingosine 1-phosphate (S1P) (21%) compared to counterpart MRL/lpr controls. sphingosine 1-phosphate nitric oxide synthase 3, endothelial cell Mus musculus