Title : Selective regulation of osteoblastic OPG and RANKL by dehydroepiandrosterone through activation of the estrogen receptor β-mediated MAPK signaling pathway.

Pub. Date : 2012 Jun

PMID : 22556124






2 Functional Relationships(s)
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1 Selective regulation of osteoblastic OPG and RANKL by dehydroepiandrosterone through activation of the estrogen receptor beta-mediated MAPK signaling pathway. Dehydroepiandrosterone TNF receptor superfamily member 11b Homo sapiens
2 DHEA seems to act selectively on osteoblasts via the dominant ER beta receptor, which mediates amplified cell viability through the MAPK signaling pathway involving pERK1/2 and upregulates the production of OPG rather than RANKL. Dehydroepiandrosterone TNF receptor superfamily member 11b Homo sapiens