Pub. Date : 2012 May
PMID : 22541398
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | OBJECTIVE: To evaluate MMP-9 and its natural tissue inhibitors of metalloproteinases (TIMP-1) levels of exhaled breath condensate (EBC) in children with asthma. | NSC638702 | matrix metallopeptidase 9 | Homo sapiens |
| 2 | RESULTS: The MMP-9 levels of EBC were found to be 57.7 +- 17.5, 35.4 +- 11.7, and 30.6 +- 3.7 ng/mL in children belonging to group 1, group 2 and group 3, respectively. | NSC638702 | matrix metallopeptidase 9 | Homo sapiens |
| 3 | Children belonging to group 1 and group 2 showed significantly higher MMP-9 levels of EBC in comparison with the controls (P < .001 and P = .047, respectively). | NSC638702 | matrix metallopeptidase 9 | Homo sapiens |
| 4 | Positive correlations were also seen between MMP-9 levels and IL-4/10 levels of EBC (r = 0.419, P = .027 and r = 0.405, P = .032, respectively) in children with asthma. | NSC638702 | matrix metallopeptidase 9 | Homo sapiens |
| 5 | CONCLUSION: We showed that MMP-9 levels of EBC are elevated in children with asthma and correlated with lung functions and other inflammatory markers such as IL-4/IL10 in EBC. | NSC638702 | matrix metallopeptidase 9 | Homo sapiens |