Title : Resveratrol enhances the antitumor effects of temozolomide in glioblastoma via ROS-dependent AMPK-TSC-mTOR signaling pathway.

Pub. Date : 2012 Jul

PMID : 22530672






2 Functional Relationships(s)
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1 Resveratrol enhances the antitumor effects of temozolomide in glioblastoma via ROS-dependent AMPK-TSC-mTOR signaling pathway. Resveratrol mechanistic target of rapamycin kinase Homo sapiens
2 CONCLUSIONS: Our findings demonstrate for the first time that resveratrol can enhance TMZ-mediated antitumor effects in GBM in vitro and in vivo, via ROS-dependent AMPK-TSC-mTOR signaling pathway. Resveratrol mechanistic target of rapamycin kinase Homo sapiens