Title : Paired nanoinjection and electrophysiology assay to screen for bioactivity of compounds using the Drosophila melanogaster giant fiber system.

Pub. Date : 2012 Apr 15

PMID : 22525737






1 Functional Relationships(s)
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1 We show specificity of the assay with methyllycaconitine citrate (MLA), a nAChR antagonist, which disrupts the PSI to DLMn connection but not the GF to TTMn connection or the function of the NMJ at the jump or flight muscles. Methyllycaconitine citrate nicotinic Acetylcholine Receptor alpha7 Drosophila melanogaster