| Protein Name | nicotinic Acetylcholine Receptor alpha7 |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 32928 |
| Gene Symbol | nAChRalpha7 |
| UniProt | Q9VWI9 (Q9VWI9_DROME), E1JJR2 (E1JJR2_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
6
Total Number of Articles : 6 |
Description |
nicotinic Acetylcholine Receptor alpha7 |
| Gene Summary |
Enables acetylcholine-gated monoatomic cation-selective channel activity. Involved in several processes, including chemical synaptic transmission; jump response; and visual behavior. Located in dendritic spine and postsynaptic density. Part of acetylcholine-gated channel complex. Is expressed in several structures, including adult head; adult periesophageal neuropils; lobula plate giant neurons; optic lobe narrow field columnar neurons; and synaptic neuropil domain. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease; esophagus squamous cell carcinoma; respiratory system cancer (multiple); and schizophrenia. Orthologous to human CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion) and CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit). [provided by Alliance of Genome Resources, Jul 2025] |
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