Pub. Date : 2012 May 18
PMID : 22517326
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | At concentrations reached in plasma after administration of salsalate or of aspirin at high doses, salicylate activates adenosine monophosphate-activated protein kinase (AMPK), a central regulator of cell growth and metabolism. | Salicylates | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 2 | At concentrations reached in plasma after administration of salsalate or of aspirin at high doses, salicylate activates adenosine monophosphate-activated protein kinase (AMPK), a central regulator of cell growth and metabolism. | Salicylates | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 3 | In AMPK knockout mice, effects of salicylate to increase fat utilization and to lower plasma fatty acids in vivo were lost. | Salicylates | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |