Title : Enforced presentation of an extrahelical guanine to the lesion recognition pocket of human 8-oxoguanine glycosylase, hOGG1.

Pub. Date : 2012 Jul 20

PMID : 22511791






2 Functional Relationships(s)
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1 Enforced presentation of an extrahelical guanine to the lesion recognition pocket of human 8-oxoguanine glycosylase, hOGG1. Guanine 8-oxoguanine DNA glycosylase Homo sapiens
2 Here we report the structure of a human 8-oxoguanine (oxoG) DNA glycosylase, hOGG1, in which a normal guanine from DNA has been forcibly inserted into the enzyme active site. Guanine 8-oxoguanine DNA glycosylase Homo sapiens