Pub. Date : 2011 Dec
PMID : 22509550
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [Effects of sodium selenite on the expressions of beta-catenin and its target cyclin D1 in colorectal cancer cells HCT 116 and SW480]. | Sodium Selenite | catenin beta 1 | Homo sapiens |
| 2 | OBJECTIVE: To explore the effects of sodium selenite on the expressions of beta-catenin and cyclin D1 in colorectal cancer cells HCT 116 and SW480. | Sodium Selenite | catenin beta 1 | Homo sapiens |
| 3 | RESULTS: Sodium selenite inhibited the expression of beta-catenin and transcription of its target such as cyclin D1. | Sodium Selenite | catenin beta 1 | Homo sapiens |
| 4 | CONCLUSIONS: Sodium selenite can lower the expression levels of beta-catenin and its target cyclin D1, during which the proteasome-mediated degradative pathway may be involved. | Sodium Selenite | catenin beta 1 | Homo sapiens |
| 5 | The decreased interaction between beta-catenin and TCF4 due to sodium selenite may be also involved in the regulation of beta-catenin signaling. | Sodium Selenite | catenin beta 1 | Homo sapiens |
| 6 | The decreased interaction between beta-catenin and TCF4 due to sodium selenite may be also involved in the regulation of beta-catenin signaling. | Sodium Selenite | catenin beta 1 | Homo sapiens |