Title : Survivin knockdown increased anti-cancer effects of (-)-epigallocatechin-3-gallate in human malignant neuroblastoma SK-N-BE2 and SH-SY5Y cells.

Pub. Date : 2012 Aug 1

PMID : 22507272






1 Functional Relationships(s)
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1 Apoptosis occurred with activation of caspase-8 and cleavage of Bid to tBid, increase in Bax:Bcl-2 ratio, mitochondrial release of cytochrome c, and increases in the expression and activity of calpain and caspase-3. tBID BH3 interacting domain death agonist Homo sapiens