Pub. Date : 2012 Jul
PMID : 22506481
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Acetylcholine-evoked [(3) H]-GABA release from SuSC crude synaptosomal preparations is calcium dependent, blocked by the voltage-sensitive calcium channel blocker, cadmium, and the nAChR antagonist mecamylamine, but is unaffected by muscarinic, glutamatergic, P2X and 5-HT3 receptor antagonists. | gamma-Aminobutyric Acid | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 2 | Approximately 50% of nAChR-mediated SuSC [(3) H]-GABA release is inhibited by alpha-conotoxin MII. | gamma-Aminobutyric Acid | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 3 | Together, these data suggest that a significant proportion of mouse SuSC nicotinic agonist-evoked GABA-release is mediated by a novel, alpha-conotoxin MII-sensitive alpha3alpha4beta2 nAChR. | gamma-Aminobutyric Acid | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 4 | The remaining alpha-conotoxin MII-resistant, nAChR agonist-evoked SuSC GABA release appears to be mediated via alpha4beta2* subtype nAChRs. | gamma-Aminobutyric Acid | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |