Title : The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2.

Pub. Date : 2012 Jun

PMID : 22493088






3 Functional Relationships(s)
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1 The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2. Glycerol diacylglycerol O-acyltransferase 1 Homo sapiens
2 Thus, our results indicate that DGAT1 and DGAT2 mediate distinct hepatic functions: DGAT2 is primarily responsible for incorporating endogenously synthesized FAs into TG, whereas DGAT1 plays a greater role in esterifying exogenous FAs to glycerol. Glycerol diacylglycerol O-acyltransferase 1 Homo sapiens
3 Thus, our results indicate that DGAT1 and DGAT2 mediate distinct hepatic functions: DGAT2 is primarily responsible for incorporating endogenously synthesized FAs into TG, whereas DGAT1 plays a greater role in esterifying exogenous FAs to glycerol. Glycerol diacylglycerol O-acyltransferase 1 Homo sapiens