Pub. Date : 2012 Apr 27
PMID : 22491658
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Risk of tacrolimus toxicity in CYP3A5 nonexpressors treated with intravenous nicardipine after kidney transplantation. | Nicardipine | cytochrome P450 family 3 subfamily A member 5 | Homo sapiens |
| 2 | Continuous intravenous nicardipine (CIVN), prescribed for posttransplant hypertension, inhibits tacrolimus metabolism by cytochrome P450 (CYP) 3A4 and could lead to tacrolimus overexposure in patients genetically lacking the alternative pathway for tacrolimus metabolism, CYP3A5. | Nicardipine | cytochrome P450 family 3 subfamily A member 5 | Homo sapiens |