Title : The role of cholesterol efflux in mechanisms of endothelial protection by HDL.

Pub. Date : 2012 Jun

PMID : 22488423






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The ATP-binding cassette (ABC) transporters ABCA1 and ABCG1, and the scavenger receptor B type 1 mediate multiple intracellular signaling pathways as well as the efflux of cholesterol and/or oxysterols in response to apoA-I/HDL. Oxysterols apolipoprotein A1 Homo sapiens
2 SUMMARY: Current data suggest that in endothelial cells ABCA1 and ABCG1 mediate the activation of intracellular signaling pathways primarily through the efflux of cholesterol and oxysterols to apoA-I/HDL. Oxysterols apolipoprotein A1 Homo sapiens