Title : Intestinal CYP3A4 and midazolam disposition in vivo associate with VDR polymorphisms and show seasonal variation.

Pub. Date : 2012 Jul 1

PMID : 22484315






1 Functional Relationships(s)
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Protein Name
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1 Vitamin D, whose levels vary seasonally with sunlight, is activated to 1alpha,25-dihydroxyvitamin D(3) that binds the vitamin D receptor (VDR) and transcriptionally regulates intestinal CYP3A4 expression. 1,25-dihydroxyvitamin D cytochrome P450 family 3 subfamily A member 4 Homo sapiens