Pub. Date : 2012 Aug 15
PMID : 22484209
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The aim of this study was to investigate the effect of vandetanib, an oral tyrosine kinase inhibitor of EGFR, VEGFR 2 and RET kinases, on the functionality of P-gp after a 24h-treatment at therapeutic concentration (2muM), and its ability to increase the cytotoxicity of chemotherapeutic agents in multidrug resistance cancer cells. | vandetanib | kinase insert domain receptor | Homo sapiens |