Title : Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling.

Pub. Date : 2012 May 18

PMID : 22474287






1 Functional Relationships(s)
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1 We tested whether niclosamide interferes with signaling cascades upstream of mTORC1, the catalytic activity of mTOR, or mTORC1 assembly. Niclosamide mechanistic target of rapamycin kinase Homo sapiens