Title : Loss of the ceramide transfer protein augments EGF receptor signaling in breast cancer.

Pub. Date : 2012 Jun 1

PMID : 22472120






2 Functional Relationships(s)
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1 We provide evidence that by regulating cellular SM levels, CERT determines the signaling output of the EGF receptor (EGFR/ErbB1), which is upregulated in approximately 70% of TNBCs. tnbcs epidermal growth factor receptor Homo sapiens
2 We provide evidence that by regulating cellular SM levels, CERT determines the signaling output of the EGF receptor (EGFR/ErbB1), which is upregulated in approximately 70% of TNBCs. tnbcs epidermal growth factor receptor Homo sapiens