Title : 111In-Labeled 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetracetic acid-Glu{PEG4-Glu[cyclo(Lys-Arg-Gly-Asp-d-Phe)]-cyclo(Lys-Arg-Gly-Asp-d-Phe)}-{PEG4-Glu[cyclo(Lys-Arg-Gly-Asp-d-Phe)]-cyclo(Lys-Arg-Gly-Asp-d-Phe)} (PEG4 = 15 amino-4,710,13-tetraoxapentadecanoic acid)

Pub. Date : 2004

PMID : 22457887






1 Functional Relationships(s)
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1 Because the integrin alphavbeta3 binds with extracellular matrix proteins (e.g., vitronectin, fibronectin) through the exposed Arg-Gly-Asp tripeptide sequence, RGD-containing peptides have been intensively studied in the past decade as a vector for imaging alphavbeta3 expression (3, 4). Glycine integrin subunit alpha V Homo sapiens