Title : Structural modification on the Lys linker enhanced tumor to kidney uptake ratios of 99mTc-labeled RGD-conjugated α-MSH hybrid peptides.

Pub. Date : 2012 May 7

PMID : 22452443






1 Functional Relationships(s)
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Protein Name
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1 The RGD motif {cyclic(Arg-Gly-Asp-D-Tyr-Asp)} was coupled to [Cys(3,4,10), D-Phe(7), Arg(11)]alpha-MSH(3-13) {(Arg(11))CCMSH} through a neutral glycine linker to eliminate the positively charged amino side chain of the Lys linker or without a linker to delete the Lys linker. D-phenylalanine pro-opiomelanocortin-alpha Mus musculus