Title : Down-regulation of Cbl-b by bufalin results in up-regulation of DR4/DR5 and sensitization of TRAIL-induced apoptosis in breast cancer cells.

Pub. Date : 2012 Aug

PMID : 22447040






1 Functional Relationships(s)
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1 Bufalin-induced down-regulation of Cbl-b contributed to the up-regulation of DR4 and DR5, which might be partially mediated by the activation of ERK, JNK and p38 MAPK. bufalin mitogen-activated protein kinase 8 Homo sapiens