Title : Synthetic lethal screen identifies NF-κB as a target for combination therapy with topotecan for patients with neuroblastoma.

Pub. Date : 2012 Mar 21

PMID : 22436457






1 Functional Relationships(s)
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1 Combination of topotecan and known NF-kappaB inhibitors (NSC 676914 or bortezomib) significantly reduced cell growth and induced caspase 3 activity in vitro. Bortezomib caspase 3 Homo sapiens