Title : Scale matters: the spatial correlation of yeast meiotic DNA breaks with histone H3 trimethylation is driven largely by independent colocalization at promoters.

Pub. Date : 2012 Apr 15

PMID : 22433953






1 Functional Relationships(s)
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1 In the budding yeast Saccharomyces cerevisiae, trimethylation of lysine 4 of histone H3 (H3K4me3) has been suggested to play a causal role in targeting Spo11 activity to small regions of preferred DSB formation called hotspots. Lysine DNA topoisomerase (ATP-hydrolyzing) Saccharomyces cerevisiae S288C