PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22433953-4	2012	In the budding yeast Saccharomyces cerevisiae, trimethylation of lysine 4 of histone H3 (H3K4me3) has been suggested to play a causal role in targeting Spo11 activity to small regions of preferred DSB formation called hotspots.	Lysine	65-71	DNA topoisomerase (ATP-hydrolyzing)	Saccharomyces cerevisiae S288C	152-157