Pub. Date : 2012 May
PMID : 22431524
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here we show that when detached from the matrix, untransformed mammary epithelial cells undergo metabolic reprogramming by markedly upregulating pyruvate dehydrogenase (PDH) kinase 4 (PDK4) through estrogen-related receptor gamma (ERRgamma), thereby inhibiting PDH and attenuating the flux of glycolytic carbon into mitochondrial oxidation. | Carbon | pyruvate dehydrogenase phosphatase catalytic subunit 1 | Homo sapiens |