Pub. Date : 2012 Apr 15
PMID : 22430736
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the current study, we found that cell-surface FcepsilonRI expression is a critical factor participant in PpL-mediated full activation of murine mast cells, which includes cytokine production, the degranulation response, and leukotriene C(4) (LTC(4)) release, and that engagement of the FcepsilonRI with IgEkappa and PpL is enough to induce tyrosine phosphorylation of ITAM in the FcRbeta- and gamma-signaling subunits. | Leukotriene C4 | Fc epsilon receptor Ia | Homo sapiens |