PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22430736-2 2012 In the current study, we found that cell-surface FcepsilonRI expression is a critical factor participant in PpL-mediated full activation of murine mast cells, which includes cytokine production, the degranulation response, and leukotriene C(4) (LTC(4)) release, and that engagement of the FcepsilonRI with IgEkappa and PpL is enough to induce tyrosine phosphorylation of ITAM in the FcRbeta- and gamma-signaling subunits. Leukotriene C4 227-240 Fc epsilon receptor Ia Homo sapiens 49-60