Title : WldS prevents axon degeneration through increased mitochondrial flux and enhanced mitochondrial Ca2+ buffering.

Pub. Date : 2012 Apr 10

PMID : 22425157






1 Functional Relationships(s)
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1 Targeting the NAD(+) biosynthetic enzyme Nmnat to mitochondria was sufficient to fully phenocopy Wld(S), and Wld(S) was specifically localized to mitochondria in synaptic preparations from mouse brain. NAD nicotinamide nucleotide adenylyltransferase 1 Mus musculus