Pub. Date : 2012 Jul
PMID : 22398368
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Additionally, suppression of DPP4 expression with siRNA induced elevated protein levels of FDPS and FDFT1, and increased cholesterol biosynthesis in WM-266-4 cells. | Cholesterol | dipeptidyl peptidase 4 | Homo sapiens |
2 | Together, the results from the present study revealed, for the first time, that 5-Aza-CdR exerts its cytotoxic effects in leukemia and melanoma cells through epigenetic reactivation of DPP4 gene and the resultant inhibition of cholesterol biosynthesis in these cells. | Cholesterol | dipeptidyl peptidase 4 | Homo sapiens |