Title : Berberine suppresses the TPA-induced MMP-1 and MMP-9 expressions through the inhibition of PKC-α in breast cancer cells.

Pub. Date : 2012 Jul

PMID : 22381172






3 Functional Relationships(s)
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1 Berberine suppresses the TPA-induced MMP-1 and MMP-9 expressions through the inhibition of PKC-alpha in breast cancer cells. Berberine matrix metallopeptidase 9 Homo sapiens
2 RESULTS: The basal levels of both the MMP-1 and MMP-9 mRNA expressions were decreased by BBR treatment in a dose-dependent manner. Berberine matrix metallopeptidase 9 Homo sapiens
3 CONCLUSION: The TPA-induced PKC-alpha phosphorylation is suppressed and then the MMP-1 and MMP-9 expressions are also inhibited by berberine. Berberine matrix metallopeptidase 9 Homo sapiens