Title : Maternal risk for Down syndrome is modulated by genes involved in folate metabolism.

Pub. Date : 2012

PMID : 22377700






2 Functional Relationships(s)
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1 The polymorphisms MTHFR c.677C>T and solute carrier family 19 (folate transporter), member 1 (SLC19A1) c.80 A>G modulate folate concentrations, whereas the 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR) c.66A>G polymorphism affects the MMA concentration. Folic Acid 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Homo sapiens
2 The polymorphisms MTHFR c.677C>T and solute carrier family 19 (folate transporter), member 1 (SLC19A1) c.80 A>G modulate folate concentrations, whereas the 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR) c.66A>G polymorphism affects the MMA concentration. Folic Acid 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Homo sapiens