Title : DNA-PKcs-mediated stabilization of p53 by JNK2 is involved in arsenite-induced DNA damage and apoptosis in human embryo lung fibroblast cells.

Pub. Date : 2012 May 5

PMID : 22366412






1 Functional Relationships(s)
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1 Here, we find that, in human embryo lung fibroblast (HELF) cells, arsenite induces the activation of dependent protein kinase catalytic subunit (DNA-PKcs), which then phosphorylates and activates c-Jun N-terminal kinases 2 (JNK2), but not JNK1. arsenite mitogen-activated protein kinase 8 Homo sapiens