Pub. Date : 2011
PMID : 22358108
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The increase in diltiazem oral bioavailability might be attributable to enhanced absorption in the small intestine via the inhibition of P-gp and to reduced first-pass metabolism of diltiazem via the inhibition of the CYP3A subfamily in the small intestine and/or in the liver rather than renal elimination of diltiazem by simvastatin. | Diltiazem | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |