Title : Glycine decarboxylase cleaves a "malignant" metabolic path to promote tumor initiation.

Pub. Date : 2012 Feb 14

PMID : 22340586






1 Functional Relationships(s)
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1 In a recent Cell article, Zhang and colleagues found that non-small cell lung cancer TICs overexpress the metabolic enzyme glycine decarboxylase, which leads to increases in pyrimidine synthesis and is critical for proliferation and tumor initiation. pyrimidine glycine decarboxylase Homo sapiens