Title : Lipin-2 reduces proinflammatory signaling induced by saturated fatty acids in macrophages.

Pub. Date : 2012 Mar 30

PMID : 22334674






1 Functional Relationships(s)
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1 Depletion of lipin-2 promotes the increased expression of the proinflammatory genes Il6, Ccl2, and Tnfalpha, which depends on the overstimulation of the JNK1/c-Jun pathway by saturated fatty acids. Fatty Acids interleukin 6 Homo sapiens