Title : Phospholipase A(2) enzymes in metabolic and cardiovascular diseases.

Pub. Date : 2012 Jun

PMID : 22327613






1 Functional Relationships(s)
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1 RECENT FINDINGS: The group 1B PLA2 digestion of phospholipids in the intestinal lumen facilitates postprandial lysophospholipid absorption, which suppresses hepatic fatty acid oxidation leading to increased VLDL synthesis, decreased glucose tolerance, and promotion of tissue lipid deposition to accentuate diet-induced hyperlipidemia, diabetes, and obesity. Fatty Acids phospholipase A2 group IB Homo sapiens