Title : Processing of anthracycline-DNA adducts via DNA replication and interstrand crosslink repair pathways.

Pub. Date : 2012 May 1

PMID : 22326903






1 Functional Relationships(s)
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1 We now show that ICL repair deficient cells (Mus81(-/-)) are hypersensitive to anthracycline-DNA adducts and ET-743, a compound which causes a chemically similar type of DNA damage. Anthracyclines MUS81 structure-specific endonuclease subunit Homo sapiens