Pub. Date : 2012 Apr
PMID : 22293538
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The G671V variant of MRP1/ABCC1 links doxorubicin-induced acute cardiac toxicity to disposition of the glutathione conjugate of 4-hydroxy-2-trans-nonenal. | Glutathione | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 2 | The G671V variant of MRP1/ABCC1 links doxorubicin-induced acute cardiac toxicity to disposition of the glutathione conjugate of 4-hydroxy-2-trans-nonenal. | Glutathione | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 3 | Glutathione forms conjugates with HNE, yielding an MRP1 substrate, GS-HNE, whose intracellular accumulation can cause toxicity. | Glutathione | ATP binding cassette subfamily C member 1 | Homo sapiens |