Title : Targeting of distinct signaling cascades and cancer-associated fibroblasts define the efficacy of Sorafenib against prostate cancer cells.

Pub. Date : 2012 Jan 26

PMID : 22278289






1 Functional Relationships(s)
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1 In 22Rv1 cells, constitutively active STAT3 and ERK are targeted by sorafenib, contrasting with PC3 cells, in which these kinases are not active. Sorafenib EPH receptor B2 Homo sapiens