Pub. Date : 2012 Nov 1
PMID : 22266871
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of Gli1 results in altered c-Jun activation, inhibition of cisplatin-induced upregulation of ERCC1, XPD and XRCC1, and inhibition of platinum-DNA adduct repair. | Cisplatin | X-ray repair cross complementing 1 | Homo sapiens |
| 2 | We therefore studied the possible relationships between Gli1, c-jun, and the upregulation of ERCC1, XPD and XRCC1 in cisplatin-resistant human ovarian cancer cells. | Cisplatin | X-ray repair cross complementing 1 | Homo sapiens |
| 3 | Use of the anti-Gli1 shRNA in cisplatin-resistant cells resulted in a block of the cell"s ability to upregulate genes in response to cisplatin treatment, including: c-jun, ERCC1, XPD and XRCC1. | Cisplatin | X-ray repair cross complementing 1 | Homo sapiens |
| 4 | Use of the anti-Gli1 shRNA in cisplatin-resistant cells resulted in a block of the cell"s ability to upregulate genes in response to cisplatin treatment, including: c-jun, ERCC1, XPD and XRCC1. | Cisplatin | X-ray repair cross complementing 1 | Homo sapiens |