Pub. Date : 2012 Jun 28
PMID : 22261337
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Pim-1 knockdown potentiates paclitaxel-induced apoptosis in human hormone-refractory prostate cancers through inhibition of NHEJ DNA repair. | Paclitaxel | Pim-1 proto-oncogene, serine/threonine kinase | Homo sapiens |
| 2 | In the absence of Pim-1, the ability of DNA repair significantly decreases when exposed to paclitaxel, leading to severe DNA damage and apoptosis. | Paclitaxel | Pim-1 proto-oncogene, serine/threonine kinase | Homo sapiens |