Pub. Date : 2012 Jan 17
PMID : 22249518
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | FGF-23 is secreted by osteoblasts and osteocytes in bone and principally targets the kidney to regulate the reabsorption of phosphate, the production and catabolism of 1,25-dihydroxyvitamin D and the expression of alpha-Klotho, an anti-ageing hormone. | 1,25-dihydroxyvitamin D | fibroblast growth factor 23 | Homo sapiens |
| 2 | FGF-23 also functions as a counter-regulatory hormone for 1,25-dihydroxyvitamin D in a bone-kidney endocrine loop. | 1,25-dihydroxyvitamin D | fibroblast growth factor 23 | Homo sapiens |