Pub. Date : 1990 Sep
PMID : 2224187
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Simvastatin, a pro-drug lactone, forms the open carboxylic acid as a major metabolite that inhibits the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Lactones | 3-hydroxy-3-methylglutaryl-CoA reductase | Homo sapiens |