Title : Inhibition of IκB kinase by thalidomide increases hepatitis C virus RNA replication.

Pub. Date : 2012 Feb

PMID : 22239529






1 Functional Relationships(s)
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1 Results revealed that while thalidomide reduced IL-8 and nuclear factor kappa B (NF-kappaB) activity by 95% and 46% in Huh-7 cells, increasing concentrations of thalidomide correlated with a linear rise in HCV replication (17-fold at 200 mum). Thalidomide C-X-C motif chemokine ligand 8 Homo sapiens