Title : OxLDL up-regulates Niemann-Pick type C1 expression through ERK1/2/COX-2/PPARα-signaling pathway in macrophages.

Pub. Date : 2012 Feb

PMID : 22232299






1 Functional Relationships(s)
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1 In addition, oxLDL-induced NPC1 expression and cellular cholesterol efflux were reversed by PPARalpha siRNA or GW6471, an antagonist of PPARalpha. GW 6471 NPC intracellular cholesterol transporter 1 Homo sapiens