Title : Structure-activity relationships for naturally occurring coumarins as β-secretase inhibitor.

Pub. Date : 2012 Jan 15

PMID : 22222157






2 Functional Relationships(s)
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Protein Name
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1 The present study was demonstrated to evaluate the effects of naturally occurring coumarins (NOCs) including simple coumarins, furanocoumarins, and pyranocoumarins on the inhibition of beta-secretase (BACE1) activity. Furocoumarins beta-secretase 1 Homo sapiens
2 Of 41 NOCs examined, some furanocoumarins inhibited BACE1 activity, but simple coumarins and pyranocoumarins did not affect. Furocoumarins beta-secretase 1 Homo sapiens