Pub. Date : 2012 Mar 13
PMID : 22210634
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Mechanisms involved in CD4 cell gains in HIV-infected patients switched to raltegravir. | Raltegravir Potassium | CD4 molecule | Homo sapiens |
2 | At 6 months, mean CD4 cell counts significantly increased in raltegravir patients from 322 to 448 cells/mul (P = 0.026) but not in controls (from 312 to 330 cells/mul; P = 0.813). | Raltegravir Potassium | CD4 molecule | Homo sapiens |
3 | In raltegravir patients, however, the proportion of naive CD4 T cells significantly increased (P = 0.014) as well as CD38 expression in these cells (P = 0.036). | Raltegravir Potassium | CD4 molecule | Homo sapiens |
4 | CONCLUSION: HIV patients with prolonged undetectable viremia on HAART experience more pronounced CD4 gains after raltegravir switching than keeping the same regimen. | Raltegravir Potassium | CD4 molecule | Homo sapiens |