Title : Neurorescue effect of rosmarinic acid on 6-hydroxydopamine-lesioned nigral dopamine neurons in rat model of Parkinson's disease.

Pub. Date : 2012 May

PMID : 22205146






2 Functional Relationships(s)
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1 Moreover, RA suppressed the increased ratio of Bax/Bcl-2 at gene level induced by 6-OHDA. rosmarinic acid BCL2 associated X, apoptosis regulator Rattus norvegicus
2 This indicates that the neurorescue effects of RA against 6-ODHA-induced degeneration of the nigrostriatal dopaminergic system were achieved by decreasing nigral iron levels and regulating the ratio of Bcl-2/Bax gene expression. rosmarinic acid BCL2 associated X, apoptosis regulator Rattus norvegicus