Title : Blockade of CRF1 receptors in the central nucleus of the amygdala attenuates the dysphoria associated with nicotine withdrawal in rats.

Pub. Date : 2012 Mar

PMID : 22182462






2 Functional Relationships(s)
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1 Blockade of CRF1 receptors in the central nucleus of the amygdala attenuates the dysphoria associated with nicotine withdrawal in rats. Nicotine corticotropin releasing hormone receptor 1 Rattus norvegicus
2 Intra-CeA administration of the CRF1 receptor antagonist R278995/CRA0450 completely prevented the mecamylamine-induced elevations in brain reward thresholds in the nicotine-treated rats and did not affect the brain reward thresholds of the saline-treated control rats. Nicotine corticotropin releasing hormone receptor 1 Rattus norvegicus